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EFV, IDV, and NFV PK parameter estimatesa
| Drug | CLint (liters/h) | CL/F (liters/h) | CVCL/F (%) | V/F (liters) | CVCL/F (%) | Ka (h−1) | CVKa (%) | tlag (h) |
|---|---|---|---|---|---|---|---|---|
| EFV | 9.0 (5.9) | 10.8 | 42 | 282 (7.2) | 7.9 | 1.39 (10) | 93 | |
| IDV | 123 (17) | 40 | 101 (24) | 88 | 1.5 (8.5) | 144 | 0.54 | |
| NFV | 41 (29) | 9 | 120 (2.8) | 2 | 0.4 (310) | 50 |
Data are given as means (percent standard errors, where available). CV, coefficient of interindividual variation; tlag, lag time.
