FIG. 2.

Effects of 14-member macrolides on the phagocytosis of apoptotic neutrophils by human alveolar macrophages (AM) in the presence of 10% fresh homologous serum (A) or medium alone (B). AM were treated with ERY or CLR at concentrations of 0.1 to 10 μg/ml, with JOS, AMP, or CEC at a concentration of 10 μg/ml for 72 h. Treatment of AM with DEX (10⁻⁷ M) was done for 24 h. The control (CTRL) represents the treatment of AM with medium containing 0.1% DMSO. Each value represents the mean ± standard deviation (error bars) of three determinations. *, P < 0.01 (versus CTRL).