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Typical HPLC chromatograms of extracts of control human serum (A), control human serum spiked with 2.5 μg of IS per ml (B), control human serum spiked with 2.5 μg of IS per ml and 3.0 μg of ribavirin per ml (C), and serum from a patient receiving ribavirin (ribavirin concentration, 2.5 μg/ml) (D).
