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Partial alignment of the deduced sequences of d,d-carboxypeptidases in VanD-type E. faecium strains 10/96A, BM4339, and BM4416 and PBPs from Streptomyces sp. strain K15 (40), Bacillus subtilis MB24 (DacF) (56), and E. coli (PBP6) (18). Conserved motifs involved in the scaffolding of the active site are indicated in boldface type. The numbers of amino acids between the NH2 terminus and motif I, motifs I and II, motifs II and III, and motif III and the COOH terminus are indicated.
