Table 2.

Predictors of Change in Hemoglobin During Hospitalization

Variable	Univariate Analyses		Final Multivariate Analysis
	Parameter Estimate (SE)	P Value	Parameter Estimate (SE)	P Value
Volume of blood draw, mL	0.073 (0.012)	<.0001	0.070 (0.011)	<.0001
Age, y	−0.069 (0.038)	.0704	−0.8211 (0.036)	.0247
Gender, male vs female	0.770 (1.266)	.5432	*	*
Length of hospitalization, days	0.468 (0.150)	.0019	§	§
Hemoglobin level on admission, g/L†	0.184 (0.033)	<.0001	0.168 (0.032)	<.0001
CCI score (0, 1, or ≥2)	−0.987 (0.719)	.1705	§	§
Intravascular volume depletion at admission‡	2.472 (1.255)	.0496	2.615 (1.203)	.0303
Chronic diseases that may cause anemia	0.833 (1.275)	.5142	*	*

^*Not included in multivariate model as it was not a univariate significant predictor (P<.2)

^†To convert g/L to g/dL, divide by 10

^‡BUN (mg/dL) to creatinine (mg/dL) ratio >25 and a calculated osmolality >295 mOsmol

^§Not included in final multivariate model as variable was not a significant predictor after controlling for other factors

CCI, Charlson comorbidity index; BUN, Blood Urea and Nitrogen