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. 2005 Jun;20(6):520–524. doi: 10.1111/j.1525-1497.2005.0094.x

Table 3.

Volumes of Blood Draw and Predicted Drops in Hemoglobin and Hematocrit Based on Clinical Scenarios

Volume of Blood Draw, mL Expected Change in Hemoglobin, g/L (95% CI)* Expected Change in Hematocrit, % (95% CI) Scenarios Resulting in the Volume of Blood Draw
10 0.7 (0.5 to 0.9) 0.19 (0.13 to 0.25) Routine labs (CBC, electrolytes, renal and coagulation profiles)
50 3.5 (2.4 to 4.6) 0.95 (0.65 to 1.25) Routine labs for 5 days
100 8.0 (4.8 to 10.2) 1.90 (1.30 to 2.50) Routine labs for 5 days, acute anemia workup, 3 sets of cardiac enzymes
200 14.0 (9.6 to 18.4) 3.80 (2.60 to 5.00) Routine labs for 10 days, 3 sets of cardiac enzymes, 3 sets of liver profile, transaminitis work-up

Divide by 10 to convert g/L to g/dL

CBC, Complete Blood Count