Table 2.
Patterns of Use of Antihypertensive Drugs Among Patients with and Without CAD
| Drug class, N (%) | Among Patients with CAD (CAD)† | Among Patients Without CAD (No CAD)‡ | ||||
|---|---|---|---|---|---|---|
| OverallN=3437 (100.0) | 1 Drug n=586 (17.0) | 2 or More Drugs n=2,610 (75.9) | Overall n=6,538 (100.0) | 1 Drug n=1,777 (27.2) | 2 or More Drugs n=3,093 (47.3) | |
| ACE inhibitors or angiotensin II inhibitors | 2,432 (70.8)* | 247 (42.2) | 2,185 (83.7) | 3,770 (57.7) | 1,162 (65.4)* | 2,608 (84.3) |
| Thiazide or loop diuretics | 1,638 (47.6)* | 52 (8.9) | 1,586 (60.8) | 2,167 (33.2) | 169 (9.5) | 1,998 (64.6) |
| β-blockers | 1,783 (51.9)* | 166 (28.3)* | 1617 (61.9)* | 1063 (16.3) | 105 (5.9) | 958 (31.0) |
| Calcium channel blockers | 1,581 (46.0)* | 79 (13.5) | 1,502 (57.5) | 1,937 (29.6) | 186 (10.5) | 1,751 (56.6) |
| Other antihypertensives | 392 (11.4)* | 11 (1.9) | 381 (14.6) | 566 (8.6) | 30 (1.7) | 536 (17.3) |
| α-blockers | 681 (19.8)* | 31 (5.3) | 650 (24.9) | 831 (12.7) | 125 (7.0) | 706 (22.8) |
Notes: Percentages of individual drug classes are given within columns: overall, and by number of drugs in regimen.
*
Statistically significantly greater percentage (P<.0001) than corresponding drug class in comparisons of patients with CAD to similar regimen in patients without CAD.
†
241 (7.0%) patients diagnosed with CAD were on no antihypertensive drugs.
‡
1,668 (25.5%) of patients without CAD were on no antihypertensive drugs.
ACE, angiotensin-converting enzyme. CAD, coronary artery disease.