Table 2.
Technique | Total | |||||
PCR | Me-PCR | |||||
K-ras+/Total Foci | K-ras+ % (95% CI) | K-ras+/Total Foci | K-ras+ % (95% CI) | K-ras+/Total Foci | K-ras+ % (95% CI) | |
PDAC | ||||||
PanIN-1A | 43/172 | 25 (19–32) | 115/266 | 43 (37–49) | 158/438 | 36 (32–41) |
PanIN-1B | 46/121 | 38 (29–47) | 27/44 | 61 (46–75) | 73/165 | 44 (37–52) |
PanIN-2–3 | 67/76 | 88 (78–94) | 7/9 | 78 (40–96) | 74/85 | 87 (78–93) |
Chronic pancreatitis | ||||||
PanIN-1A | 20/159 | 13 (8–19) | 1/17 | 6 (0–31) | 21/176 | 12 (8–18) |
PanIN-1B | 12/121 | 10 (5–17) | - | - | 12/121 | 10 (5–17) |
PanIN-2–3 | 1/35 | 3 (0–17) | 2/15 | 13 (2–42) | 3/50 | 6 (2–18) |
Normal pancreas | ||||||
PanIN-1A | 30/243 | 12 (9–17) | 9/51 | 18 (9–31) | 39/294 13 | (10–18) |
PanIN-1B | 6/173 | 3 (1–8) | 8/17 | 47 (24–71) | 14/190 | 7 (4–12) |