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. 2005 Jan;7(1):57–66. doi: 10.1593/neo.04406

Figure 2.

Figure 2

In vivo growth and invasive behavior of malignant human keratinocytes. (A) HaCaT II-4 (a and d), HaCaT A5-RT3 (b and e), and CasKi (c and f) cells were transplanted for 3 weeks into WT (a–c) and PAI-1-/- (d–f) nude mice. (B) HaCaT II-4 (a and c) and HaCaT A5-RT3 (b and d) cells were transplanted for 3 weeks into WT (a and b) and PAI-1-/- (c and d) Rag-1-/- mice. Histological sections were stained with hematoxylin and eosin. C = carcinoma cells; G = collagen gel; H = host connective tissue. Original magnification, x 200.