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. 2005 Jan;7(1):57–66. doi: 10.1593/neo.04406

Figure 3.

Figure 3

Morphometric assessment of tumor cell invasion implanted into nude or Rag-1-/- mice. HaCaT II-4 (a and d), HaCaT A5-RT3 (b and e), and CasKi (c) tumor cells were grafted for 3 weeks into PAI-1-/- (white bars) and control (black bars) mice in nude (a–c) or Rag-1-/- (d and e) background. Tumor cell invasion was estimated by measuring the distance between the top of the tumor to the deepest front of tumor spread. n = number of animals per group. *P ≤ .02, ***P ≤ .0001, Student's t test. Data are expressed as mean ± standard error of the mean.