TABLE 1.
Ratios (medians) and IQRs of the concentrations of indinavir, nelfinavir, lopinavir, and ritonavir in CSF, semen, and LN tissue compared to those in plasma
| Sanctuary site | Concn ratio (IQR)a
|
|||
|---|---|---|---|---|
| IDV | NFV | LPV | RTV | |
| CSF | 0.17 (0.10-0.49) | 0 | 0 | 0 |
| Semen | 1.9 (1.07-3.94) | 0.08 (0.06-0.10) | 0.07 (0.01-0.45) | 0 |
| LN tissue | 2.07 (1.02-3.67) | 0.58 (0.27-0.84) | 0.21 (0.15-0.26) | 0.64 (0-1.15) |
IDV, indinavir; NFV, nelfinavir; LPV, lopinavir; RTV, ritonavir.