TABLE 2.
MICs for A. phagocytophila strains
| Antibiotica | MIC (μg/ml) for strain:
|
|||||||
|---|---|---|---|---|---|---|---|---|
| Webster | MRK | Spooner | NY8 | 97E13 | Sawyer | 98E4 | Bayfield | |
| Ampicillin | >128 | >128 | >128 | >128 | >128 | >128 | >128 | >128 |
| Ceftriaxone | >128 | >128 | >128 | >128 | >128 | >128 | >128 | >128 |
| Amikacin | >64 | >64 | >64 | >64 | >64 | >64 | >64 | >64 |
| Chloramphenicol | 4 | 4 | 2 | 2 | 8 | 2 | 4 | 2 |
| Erythromycin | >16 | >16 | >16 | >16 | >16 | >16 | >16 | >16 |
| Azithromycin | >16 | >16 | >16 | >16 | >16 | >16 | >16 | >16 |
| Doxycycline | ≤0.03 | ≤0.03 | ≤0.03 | ≤0.03 | ≤0.03 | ≤0.03 | ≤0.03 | ≤0.03 |
| Rifampin | ≤0.03 | ≤0.03 | ≤0.03 | ≤0.03 | ≤0.03 | ≤0.03 | ≤0.03 | ≤0.03 |
| Levofloxacin | 0.5 | 0.25 | 0.06 | 0.125 | 0.5 | 0.5 | 0.5 | 0.5 |
| Sulfamethoxazole-trimethoprimb | 50/10 | 25/5 | 100/20 | 25/5 | 25/5 | 50/10 | 100/20 | 100/20 |
a
Ampicillin, ceftriaxone, amikacin, erythromycin, rifampin, and sulfamethoxazole-trimethoprim were obtained from Sigma-Aldrich Chemical Co. (St. Louis, Mo.); azithromycin and doxycycline were obtained from Pfizer (Brooklyn, N.Y.); chloramphenicol was obtained from Parke-Davis (Morris Plains, N.J.); and levofloxacin was obtained from Ortho-McNeil (Spring House, Pa.).
b
Sulfamethoxazole-trimethoprim was used at a 5:1 (wt/wt) ratio.