Figure 6.

Duplicated Motifs within the COP1′ Protein.

(A) Motifs within Arabidopsis COP1 required for repression of photomorphogenic development in darkness (modified from that shown in Torii et al., 1998). COP1 contains a Zn binding RING domain (RING) and a coiled-coil domain (COIL) at the N terminus between which is found a cytoplasmic localization signal (CLS). A region containing at least five WD-40 repeats (WD-40) is found at the C terminus with a nuclear localization signal (NLS) located toward the middle of the protein.

(B) Motifs within pea COP1′. The duplicated region within COP1′ contains part of the cytoplasmic localization signal, the coiled-coil domain, and the region containing the nuclear localization signal. COP1′ contains intact N- and C-terminal motifs.

(+), position of NLS as shown in Figure 6A.