Fig. 2. Structure of KT-7. (A) Secondary structure with residues in the C-stem labeled red and the NC-stem blue. The bulged nucleotide is green. (B) Schematic representation of the relative base-stacking and pairing interactions. A black triangle represents an A-minor interaction. (C) Three-dimensional representation of KT-7 with the phosphate backbone of the kinked strand in orange and the unkinked strand in yellow. Hydrogen bonds are indicated by dashed lines. (D) Atomic details of individual base–base and base–backbone hydrogen bonds.