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Superimposed stereo views into the major groove of hairpin molecular structures derived by the original authors, in yellow, and of the final molecular structures derived from the elastic curve approach, in red: (A) GTTA (1ac7); (B) AAA (1bjh); (C) UUCG (1b36). These views are representative of the three main classes of molecules under study: DNA tetraloop, DNA triloops and RNA tetraloops. The sugar–phosphate chain is highlighted in bold.
