Table 4.

Independent Predictors Identified by Multivariate Analysis

	Crude	Adjusted
Variable	Odds Ratio (95% CI)	Beta	Odds Ratio (95% CI)	Points *
Intercept		4.
Age, 60 to 69	2.0 (1.3 to 3.0)	0.75	2.1 (1.3 to 3.4)	3
Age, 70 or more	1.3 (0.9 to 1.9)	0.56	1.7 (1.1 to 2.8)	2
Female	2.4 (1.6 to 3.6)	0.83	2.3 (1.5 to 3.5)	3
Neither African-American nor East Asian	1.4 (0.9 to 2.2)	0.56	1.7 (1.1 to 2.9)	2
East Asian (Chinese, Korean, Japanese)	2.4 (0.8 to 7.5)	1.46	4.3 (1.2 to 14.8)	6
No history of other ACE inhibitors	1.2 (0.8 to 1.8)	0.88	2.4 (1.3 to 4.4)	3
History of ACE inhibitor-induced cough	14 (6.1 to 33.4)	3.38	29 (10.4 to 82.5)	13

The risk score for an individual patient was determined by assigning points for each factor present and summing. The resulting risk score was then used in Table 5 to estimate the probability of ACE inhibitor-induced cough. The reference group for variable “Age, 60 to 69” is the group “Age less than 60 or equal to or greater than 70.” That for “Age, 70 or more” is the group “Age less than 70.” That for “Neither African-American nor East Asian” is the group “African-American or East Asian.” That for “East Asian” is the group “Ethnicity other than African-American or East Asian.” Model R²was 0.14.

^* Calculated by dividing the beta coefficient by 0.26 and rounding to the nearest integer.

ACE, angiotensin-converting enzyme; CI, confidence interval.