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. 2004 Jun;19(6):676–683. doi: 10.1111/j.1525-1497.2004.30328.x

Table 1.

Classification of ACE Inhibitor Therapy Dose Range (mg/day)

ACE Inhibitor Therapy Low Medium High
Benazepril HCl * 5 6 to 19 20
Captopril 38 39 to 149 150
Cilazapril * 1.25 1.26 to 4 5
Enalapril maleate 5 6 to 19 20
Fosinopril sodium * 5 6 to 19 20
Lisinopril 5 6 to 19 20
Perindopril erbumine * 2 3 to 7 8
Quinapril HCl 10 11 to 39 40
Ramipril * 2.5 2.6 to 9 10
*

High doses based on the highest recommended maintenance dose in the Compendium of Pharmaceuticals and Specialties.24

Analysis repeated for lisinopril high dose of 32.5 mg or greater and low dose 5 mg of less.

High dose based on the ACE inhibitor target doses recommended by the Agency for Health Care Policy and Research for the management of heart failure.23

High dose based on randomized controlled trial (RCT) evidence.

ACE, angiotensin-converting enzyme.