Table 2.
The Management of Dyslipidemia in Adults with Chronic Kidney Disease
| Dyslipidemia | Goal | Initiate | Increase | Alternative |
|---|---|---|---|---|
| TG ≥ 500 mg/dl | TG < 500 mg/dl | Lifestyle changes | Lifestyle changes + fibrate or niacin | Fibrate or niacin |
| LDL-C 100–129 mg/dl | LDL-C < 100 mg/dl | Lifestyle changes | Lifestyle changes + low-dose statin | Bile acid sequestrant or niacin |
| LDL-C ≥ 130 mg/dl | LDL-C < 100 mg/dl | Lifestyle changes + low-dose statin | Lifestyle changes + max-dose statin | Bile acid sequestrant or niacin |
| TG ≥ 200 mg/dl and non-HDL-C ≥ 130 mg/dl | Non-HDL-C < 130 mg/dl | Lifestyle changes + low-dose statin | Lifestyle changes + max-dose statin | Fibrate or niacin |
HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; TG, triglycerides.
Reproduced with permission from K/DOQI guidelines on treating dyslipidemia.3