Table 1.
Characteristics of Adult Patients at First Treatment with an Antipsychotic Drug
| First Antipsychotic Drug Prescribed | |||
|---|---|---|---|
| Characteristic | Olanzapine (n = 438) | Risperidone (n = 482) | Typical Phenothiazine (n = 2,195) |
| Female gender, % | 49.3 | 51.9 | 57.8 |
| Black race, % | 45.1 | 47.9 | 47.9 |
| Mean age, y (SD) | 42.9 (12.0) | 42.4 (14.5) | 42.6 (14.9) |
| Mean number of years on drug (SD) | 2.3 (1.2) | 2.3 (1.5) | 6.0 (4.8) |
| Schizophrenia, %* | 35.2 | 22.6 | 0.2 |
| Depression, % | 17.1 | 18.5 | 5.0 |
| Anxiety, % | 10.5 | 11.0 | 5.6 |
| Personality disorder, % | 14.4 | 11.4 | 3.1 |
| Dementia, % | 6.2 | 9.3 | 1.6 |
| Alcohol dependence, % | 29.0 | 28.0 | 6.8 |
| Drug abuse, % | 15.3 | 12.7 | 1.8 |
| Obesity, % | 10.7 | 13.1 | 4.7 |
| Benztropine, % | 46.6 | 41.3 | 20.4 |
| Primary care visits (mean, SD) | 5.6, 11.7 | 5.3, 10.4 | 0.4, 2.1 |
| Mental health visits (mean, SD) | 66.2, 132.4 | 36.6, 100.9 | 0.5, 6.1 |
| Emergency room visits (mean, SD) | 9.8, 14.9 | 9.8, 16.2 | 2.0, 5.0 |
| Mean weight, lb (SD) | 185.4 (46.6) | 187.6 (50.6) | 168.6 (45.2) |
| ≥7% weight gain during the first year of antipsychotic drug treatment, % | 39.8 | 37.0 | 24.9 |
| New onset diabetes in the first year of antipsychotic drug treatment, % | 8.0 | 3.5 | 3.2 |
*
All diagnoses were those available in Patients' electronic records prior to the visit in which the first antipsychotic drug was prescribed.
SD, standard deviation.