Table 2.

Independent Multivariable Predictors of ≥ 7% Weight Gain in the First Year of Antipsychotic Drug Therapy

Independent Variables	OR	95% CI	χ2	P Value
Olanzapine use	2.8	1.7 to 4.6	17.8	<.0001
Risperidone use	2.3	1.5 to 3.4	15.4	<.0001
Schizophrenia	0.7	0.4 to 1.2	1.8	.2
Depression	1.2	0.8 to 1.7	0.7	.4
Anxiety	1.2	0.8 to 1.9	1.1	.3
Personality disorder	0.8	0.5 to 1.5	0.5	.5
Dementia	0.8	0.4 to 1.4	0.8	.4
Alcohol abuse	1.1	0.7 to 1.6	0.1	.8
Drug abuse	1.1	0.6 to 2.0	0.02	.9
Obesity	1.3	0.8 to 2.0	1.2	.3
Cognitive dysfunction	1.1	0.8 to 1.6	0.2	.6
Primary care visits	0.98	0.97 to 1.0	0.28	.1
Mental health visits*	1.0	1.0 to 1.01	0.6	.4
Emergency visits	1.0	1.00 to 1.02	2.5	.1
Baseline weight, lb	0.99	0.96 to 0.99	38.2	<.0001

^*Odds ratio for 10 visits.

OR, adjusted odds ratio; CI, confidence interval.