TABLE 2.
MIC multiple | Log10 CFU/ml at 3 h with: |
||||
---|---|---|---|---|---|
Levofloxacin | Ciprofloxacin | Azithromycin | Erythromycin | Doxycycline | |
L. pneumophila L-1033 (SD, 0.29 log10 CFU/ml) | |||||
0 | 7.24 | 7.37 | 7.59 | 7.22 | 7.07 |
1 | 6.74** | 6.94** | 7.23** | 7.10 | 6.79 |
5 | 4.65** | 5.19** | 6.90** | 6.98 | 6.67 |
10 | 4.06** | 4.45** | 6.87** | 6.68 | 6.74 |
L. pneumophila L-1043 (SD, 0.18 log10 CFU/ml) | |||||
0 | 6.80 | 6.63 | 6.54 | 6.80 | 6.85 |
1 | 6.17** | 6.74 | 6.32 | 6.68 | 6.68 |
5 | 3.94** | 6.52 | 6.08** | 6.64 | 6.35** |
10 | 3.24** | 6.18** | 5.97** | 6.61 | 6.41** |
Three to five assays were performed for strain L-1033; two to three assays were performed for strain L-1043. Asterisks denote statistical difference from the control (0 times the MIC).
P < 0.01.