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. 2003 Mar;47(3):1081–1087. doi: 10.1128/AAC.47.3.1081-1087.2003

TABLE 2.

Microbial growth of L. pneumophila L-1033 and L-1043 following exposure to levofloxacin, ciprofloxacin, azithromycin, erythromycin, and doxycycline at various concentrationsa

MIC multiple Log10 CFU/ml at 3 h with:
Levofloxacin Ciprofloxacin Azithromycin Erythromycin Doxycycline
L. pneumophila L-1033 (SD, 0.29 log10 CFU/ml)
    0 7.24 7.37 7.59 7.22 7.07
    1 6.74** 6.94** 7.23** 7.10 6.79
    5 4.65** 5.19** 6.90** 6.98 6.67
    10 4.06** 4.45** 6.87** 6.68 6.74
L. pneumophila L-1043 (SD, 0.18 log10 CFU/ml)
    0 6.80 6.63 6.54 6.80 6.85
    1 6.17** 6.74 6.32 6.68 6.68
    5 3.94** 6.52 6.08** 6.64 6.35**
    10 3.24** 6.18** 5.97** 6.61 6.41**
a

Three to five assays were performed for strain L-1033; two to three assays were performed for strain L-1043. Asterisks denote statistical difference from the control (0 times the MIC).

**

P < 0.01.