TABLE 4.

PAE duration by the Q and C&G methods^a

MIC multiple	Q PAE (h) with:			C&G PAE (h) with:
	Levofloxacin	Ciprofloxacin	Azithromycin	Levofloxacin	Ciprofloxacin	Azithromycin
L. pneumophila L-1033b
1	0.1	1.1	−1.7	−0.7	−0.5	−2.5
5	3.9**	4.9**	−1.3	1.7	1.9	−2.9
10	5.8**	4.3**	4.6**	4.0	2.1	1.5
L. pneumophila L-1043c
1	1.1	1.0	0.7	0.2	1.0	0.2
5	10.5**	1.5	1.2	8.1**	1.5	0.6
10	10.4**	0.9	0.9	8.4**	1.0	0.2

^aThree to five assays were performed for strain L-1033; two to three assays were performed for strain L-1043. Asterisks denote statistical difference from the control (0 times the MIC).

^**P < 0.01.

^bSD for Q and C&G PAE, 2.5 and 3.9 h, respectively.

^cSD for Q and C&G PAE, 2.0 and 1.8 h, respectively.