Table 2.
Drug and ion sensitivities
| Strain | Class | 37°C | pH 7.5 | pH 2.5 | Ca2+ | Mn2+ | Cd2+ | Zn2+ | Caffeine | FK506 | Hygromycin |
|---|---|---|---|---|---|---|---|---|---|---|---|
| luv1Δ (strain YMC4) | − | − | − | + | − | − | − | − | − | − | |
| vps1 | F | +/− | − | − | + | + | +/− | + | + | − | − |
| pep5/vps11 | C | − | − | − | − | + | + | − | − | − | − |
| vps15 | D | − | − | − | + | + | + | − | − | − | − |
| vps27 | E | +/− | + | − | + | + | + | − | − | + | − |
| vps45 | D | − | − | − | +/− | +/− | + | − | + | − | − |
Cell growth on plates with various added substances was assayed as in Figure 2. (+) Appreciable growth under these conditions compared with wild type; (−) no growth; (+/−) some growth. Classes are as described by Raymond et al. (1992). See Figure 2 for concentrations and conditions, calcium chloride 800 mM in synthetic complete dextrose medium.