TABLE 2.
MICs of aminoglycosides, carbenicillin, and tetracycline for P. aeruginosa mutants lacking selected outer membrane channel proteins
| Strain | Phenotype | MIC (μg/ml)a
|
|||||
|---|---|---|---|---|---|---|---|
| Km | Gm | Sm | Tm | Cb | Tc | ||
| H911 | Parent | 100 | 0.8 | 8 | 0.25 | 50 | 1.3 |
| H958 | OpmG− | 13 | 0.1 | 1 | 0.063 | 50 | 25 |
| H966 | OpmH− | 13 | 0.4 | 2 | 0.031 | 50 | 25 |
| H960 | OpmI− | 13 | 0.2 | 0.5 | 0.063 | 100 | 13 |
| H957 | OpmA− | 100 | 0.8 | 8 | 0.25 | 100 | 13 |
| H963 | OpmD− | 100 | 0.8 | 4 | 0.25 | 100 | 25 |
| H962 | OpmL− | 50 | 0.8 | 8 | 0.5 | 100 | 25 |
a
Abbreviations: Km, kanamycin; Gm, gentamicin; Sm, streptomycin; Tm, tobramycin; Cb, carbenicillin; Tc, tetracycline.