TABLE 3.

Induction of efflux genes by tigecycline and tetracycline^a

Treatment	Fold change
	mexZ	mexX	mexY	oprM
TGC, 1 μg/ml	4.52	13.43	12.85	0.9
TGC, 2 μg/ml	5.28	15.48	13.34	0.63
TGC, 4 μg/ml	10.92	14.85	11.45	0.47
TET, 4 μg/ml	4.93	15.81	14	0.78

^aValues represent fold changes in transcript levels detected compared to untreated control samples and are averages of two biological replicates. TGC, tigecycline; TET, tetracycline.