TABLE 2.
Activities of ciprofloxacin and garenoxacin against clinical isolates of S. aureus
| Test compound | Ciprofloxacin phenotype of isolates | No. of isolates | No. of spa types | MIC (μg/ml)
|
MPC (μg/ml)
|
MPC/MIC ratio | ||||
|---|---|---|---|---|---|---|---|---|---|---|
| 90% | Mode | Range | 90% | Mode | Range | |||||
| Ciprofloxacin | Susceptible | 20 | 15 | 0.6 | 0.4 | 0.2-0.6 | 8 | 3-4 | 2-12 | 13 |
| Garenoxacin | Susceptible | 20 | 15 | 0.03 | 0.015 | 0.005-0.03 | 0.4 | 0.3-0.4 | 0.07-0.8 | 13 |
| Resistant | 22 | 10 | 3.2 | 0.8-1.2 | 0.04-4.8 | >19.6 | 9.6-12.8 | 3.2->28.8 | >6 | |