FIG. 3.

CAT activities in Jurkat cells infected with HIV-1 CAT reporter viruses. Cultures were infected with HIV-1 recombinant CAT viruses expressing envelope glycoproteins from a laboratory-adapted T-tropic virus, HXBc2 (A), and a primary dualtropic virus, 89.6 (B), and then maintained in the absence or presence of WM5 or WM5E at the concentrations shown. Four days later, CAT activity in cell lysates was measured. The results are reported as percent conversion (% conv.) of [¹⁴C]chloramphenicol to acetylated forms above the spots. A representative experiment of two performed is shown.