TABLE 2.

MICs of β-lactam molecules and quinolones for clinical isolates of serovar Wien, recipient E. coli strains, and E. coli transformants

Antibiotica	MIC (μg/ml)
	Serovar Wien clinical isolate			E. coli recipient		E. coli NM554 transformant			E. coli BZB 1170 (OmpF−) transformant
	186	468	1107	NM554	BZB1107 (OmpF−)	SW468b	SW1107c	SW1107d	SW468b	SW1107c	SW1107d
Amoxicillin	2	>1,024	>1,024	2	8	1,024	1,024	1,024	>1,024	>1,024	>1,024
Amoxicillin-CLA	1	>1,024	>1,024	2	8	1,024	1,024	1,024	>1,024	>1,024	>1,024
Ticarcillin	4	>1,024	>1,024	2	16	1,024	1,024	1,024	1,024	1,024	>1,024
Ticarcillin-CLA	2	>1,024	>1,024	2	16	1,024	1,024	128	1,024	1,024	512
Piperacillin	2	>1,024	>1,024	1	0.5	64	64	512	32	32	256
Piperacillin-TAZ	1	1,024	>1,024	0.5	0.5	16	16	0.5	4	4	2
Cephalothin	2	>1,024	1,024	1	32	256	512	512	>1,024	>1,024	>1,024
Cefoxitin	1	1,024	256	1	32	128	128	1	128	128	16
Cefotetan	<0.06	512	256	<0.06	4	64	32	0.12	256	256	8
Cefotaxime	<0.06	512	1,024	<0.06	<0.06	32	64	16	64	64	128
Cefotaxime-CLA	<0.06	512	128	<0.06	<0.06	32	32	<0.06	64	64	0.12
Ceftazidime	0.25	512	256	<0.06	0.5	128	256	2	128	128	4
Ceftazidime-CLA	0.25	512	256	<0.06	0.5	128	128	0.25	128	128	1
Cefepime	<0.06	32	512	<0.06	0.12	0.5	1	8	4	4	256
Cefepime-CLA	<0.06	32	64	<0.06	0.06	1	1	<0.06	4	4	4
Cefpirome	<0.06	128	512	<0.06	<0.06	1	1	4	8	8	128
Imipenem	0.5	32	0.5	0.5	0.5	1	1	1	16	8	4
Nalidixic acid	4	2	2	2	2	2	2	2	1	1	2
Norfloxacin	0.06	0.12	0.06	<0.03	0.06	<0.03	<0.03	<0.03	0.06	0.06	0.06
Ciprofloxacin	<0.03	<0.03	<0.03	<0.03	<0.03	<0.03	<0.03	<0.03	<0.03	<0.03	<0.03

^aCLA, clavulanic acid (2 μg/ml); TAZ, tazobactam (4 μg/ml).

^bTransformants selected on agar plates containing ceftazidime, cefoxitine, or cefotaxime.

^cTransformants selected on agar plates containing ceftazidime or cefoxitine.

^dTransformants selected on agar plates containing cefotaxime.