TABLE 4.

Drug binding affinity to double-stranded DNA hairpin oligonucleotides

Drug	Apparent Kd (μM)
	5′-TGGCCTCC 3′-ACCGGACC	5′-TAACCTCC 3′-ATTGGACC
PD0117962	329.5 ± 38.7	369.3 ± 55.0
PD0129603	342.3 ± 47.2	336.4 ± 40.3
PD0163449	427.9 ± 73.1	438.3 ± 61.6
Ciprofloxacin	320.2 ± 64.6	348.0 ± 68.0
PD0164488	287.0 ± 43.0	362.3 ± 58.0
Difloxacin	346.4 ± 34.2	534.6 ± 58.6
Ofloxacin	362.0 ± 49.1	465.4 ± 30.2
Enoxacin	264.0 ± 38.3	335.6 ± 51.0
Norfloxacin	309.0 ± 53.6	333.9 ± 45.9
Pefloxacin	291.8 ± 30.1	322.9 ± 67.6
Oxolinic acid	504.4 ± 145.3	335.9 ± 68.4
Piromidic acid	497.3 ± 106.3	681.1 ± 183.2