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Accumulation of radioactive clarithromycin (A, C, and E) and azithromycin (B, D, and F) in representative strains in the presence (▪) or absence (⧫) of CCCP. CCCP treatment increases radioactive antibiotic accumulation in baseline and high-level macrolide-resistant strains, while it had no effect in the hypersusceptible strain because the accumulation level was already high. OD600, optical density at 600 nm.
