TABLE 2.

Kill kinetic results

Drug	Dose	No. of strains with indicated change in log10 CFU/mla at:
		3 h			6 h			12 h			24 h
		−1	−2	−3	−1	−2	−3	−1	−2	−3	−1	−2	−3
Ranbezolid	4× MIC	7	2	0	11	3	1	12	11	3	12	12	9
	2× MIC	6	0	0	7	1	0	12	8	2	12	11	5
	MIC	4	0	0	5	0	0	10	5	0	10	8	3
Linezolid	4× MIC	6	2	0	11	4	0	12	10	1	12	12	9
	2× MIC	5	0	0	8	2	0	12	6	1	12	12	6
	MIC	3	0	0	3	1	0	9	5	0	11	7	2
Vancomycin	4× MIC	11	4	0	12	7	0	12	12	8	12	12	12
	2× MIC	11	4	0	12	6	0	12	12	8	12	12	12
	MIC	10	2	0	12	4	0	12	12	7	10	11	10
Teicoplanin	4× MIC	7	0	0	9	0	0	12	9	1	12	12	10
	2× MIC	6	0	0	7	0	0	12	8	1	12	12	10
	MIC	4	0	0	6	0	0	12	8	1	11	10	7
Quinupristin- dalfopristin	4× MIC	12	12	10	12	12	10	12	12	12	12	12	12
	2× MIC	12	12	10	12	12	10	12	12	12	12	12	12
	MIC	12	12	9	12	12	10	12	12	8	11	7	7
Amoxicillin- clavulanate	4× MIC	12	4	0	12	6	1	12	12	7	12	12	11
	2× MIC	12	4	0	12	6	1	12	12	7	12	12	11
	MIC	8	3	0	12	3	1	12	12	4	12	12	10
Ciprofloxacin	4× MIC	12	4	0	12	10	0	12	12	9	12	12	11
	2× MIC	11	1	0	12	8	0	12	12	8	12	12	11
	MIC	7	0	0	12	1	0	12	12	6	10	10	6
Levofloxacin	4× MIC	11	3	0	12	10	0	12	12	8	12	12	11
	2× MIC	11	2	0	12	9	0	12	12	8	12	12	11
	MIC	6	0	0	11	2	0	11	10	3	12	10	6
Gatifloxacin	4× MIC	12	4	0	12	10	0	12	12	8	12	12	11
	2× MIC	12	3	0	12	8	0	12	12	7	12	12	11
	MIC	7	0	0	12	3	0	12	10	4	12	12	7
Moxifloxacin	4× MIC	12	3	0	12	8	0	12	12	8	12	12	11
	2× MIC	10	0	0	12	6	0	12	12	7	12	12	11
	MIC	5	0	0	9	1	0	10	9	2	12	11	9
Erythromycinb	4× MIC	6c	1	0	8	2	0	9	9	4	9	9	9
	2× MIC	6	0	0	7	2	0	9	8	2	9	9	8
	MIC	4	0	0	5	0	0	8	6	0	7	6	2

^a−1, 90% killing; −2, 99% killing; −3, 99.9% killing.

^bOnly nine strains for which erythromycin MICs were ≤4.0 μg/ml were tested.