Table 3.
The effect of CD, Lan A, and Jasp on IMV and EEV entry
| Concentration (μM) | CDa | %b | Lan Aa | % | Jaspa | % |
|---|---|---|---|---|---|---|
| IMV | ||||||
| 0 | 70.5 ± 20.8 | 100 | 70.5 ± 20.8 | 100 | 70.5 ± 20.8 | 100 |
| 0.5 | 26.8 ± 10.9 | 38 | 17.3 ± 11.6 | 25 | 32.7 ± 14.1 | 46 |
| 1 | 19.4 ± 10.4 | 28 | 17.0 ± 11.3 | 24 | 27.7 ± 16.7 | 39 |
| 2 | 12.0 ± 5.9 | 17 | 10.4 ± 7.4 | 15 | 20.3 ± 11.4 | 29 |
| 4 | NDc | ND | 3.7 ± 4.9 | 5 | 13.6 ± 7.1 | 19 |
| EEV | ||||||
| 0 | 68.2 ± 23.3 | 100 | 68.2 ± 23.3 | 100 | 68.2 ± 23.3 | 100 |
| 0.5 | 61.8 ± 29.4 | 91 | 59.6 ± 18.5 | 87 | 67.5 ± 25.4 | 99 |
| 1 | 66.2 ± 27.6 | 97 | 65.5 ± 25.0 | 96 | 72.8 ± 21.7 | 107 |
| 2 | 65.2 ± 29.0 | 96 | 67.9 ± 30.0 | 99 | 70.2 ± 26.9 | 103 |
| 4 | 63.5 ± 26.8 | 93 | 67.7 ± 25.0 | 99 | 59.0 ± 20.3 | 87 |
a
Average number of cores and S.D.s per cell after infection with IMV at MOI 50 or at EEV at MOI 20 and after pretreatment with CD, Lan A, and Jasp at the indicated concentrations; n = 30. In each case, the number of cores in the cytoplasm of 15 “small” and 15 “big” HeLa cells were counted.
b
Percentage of control, the average amount of cores in untreated cells was taken as 100%.
c
ND, not done.