Table 4.
The effect of nocodazole and taxol on IMV and EEV entry
| Treatment | IMV
|
EEV
|
||
|---|---|---|---|---|
| No. of coresa | %b | No. of cores | % | |
| Controlc | 59.5 ± 20.9 | 100 | 68.8 ± 23.3 | 100 |
| Nocodazole (10 μM) | 54.0 ± 20.0 | 91 | 69.1 ± 25.1 | 101 |
| Taxol (2 μM) | 61.5 ± 22.9 | 103 | 68.6 ± 25.4 | 101 |
Average number of cores and S.D.s per cell after infection with IMV (MOI 50) or EEV (MOI 20); n = 30. In each case the amount of cores in the cytoplasm of 15 “small” and 15 “big” HeLa cells were counted.
Percentage of control, the average amount of cores in untreated cells was taken as 100%.
Control signifies no drug treatment.