Table 2.
Risk of nasopharyngeal carcinoma associated with PIGR1739C→T genotype according to different models of inheritance.
| THAI OR (95%CI) |
CHINESE OR (95%CI) |
TOTAL OR (95%CI) |
ETHNIC GROUP ADJUSTED OR (95%CI) |
AGE, SEX AND ETHNIC GROUP ADJUSTED OR (95%CI) |
|
| C codominance, T wild type | |||||
| CC | 1.63(0.42–6.55) | 4.80(0.57–105.53) | 2.20(0.79–6.44) | 2.59(0.85–7.48) | 2.53(0.68–13.43) |
| CT | 0.78(0.18–3.35) | 2.13(0.22–50.65) | 0.81(0.27–2.48) | 1.08(0.34–3.53) | 1.24(0.23–8.00) |
| TT | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 |
| C dominance, T wild type | |||||
| TT | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 |
| CC or CT | 1.29(0.33–5.04) | 3.77(0.46–81.87) | 1.60(0.58–4.62) | 1.96(0.66–5.70) | 1.99(0.51–10.40) |
| C recessive, T wild type | |||||
| CT or TT | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 |
| CC | 2.02(1.10–3.17)1 | 2.51(1.05–6.09)1 | 2.65(1.73–4.08)3 | 2.71(1.72–4.23)3 | 2.42(1.51–4.29)2 |
CC and TT are the homozygous C and T at nucleotide 1739, respectively. CT is the heterozygous at nucleotide 1739. Total is Thai, Chinese and Thai-Chinese cases and controls. OR (95%CI) is odd ratios and 95% confidence interval between allele and compared allele, 1 p < 0.05, 2 p < 0.001, 3 p < 0.00001