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HPV-16 and HPV-31 cell internalization. HPV-16 VLPs (A to E) and HPV-31 VLPs (F to J) are shown. The electron micrographs show cells after incubation with VLPs at 4°C (A and G) and at 37°C for 10 min (B, F, and H), 20 min (C and I), and 1 h (D, E, and J). Bars, 150 nm. Cav, caveolae; Cla, clathrin-coated vesicles.
