Table 3.

Association of clinical variables with HRQL in 186 African Americans

Clinical Variable	Physical Functioning	Social Functioning	Mental Health	General Health
Measured clinical abnormality
BMI (kg/m2)
30–35	−11.6*	−2.8	−5.3	−7.0
>35	−17.4†	−11.3*	−3.7	−9.7*
Elevated HbA1c§	6.2	0.8	−3.4	0.2
Elevated blood pressure‖	7.8	5.2	1.3	−1.9
Impaired renal function¶	−12.5*	−6.4	−0.3	−8.6*
Abnormal lipids#	0.5	−4.1	−0.9	−6.2
Uses insulin	−9.2*	−2.2	−1.7	−1.1
Charlson Comorbidity Index**	−7.7‡	−9.4‡	−2.9	−3.9†

^*P < .05.

^†P < .01.

^‡P < .001.

^§Defined as >9.0%.

^‖Defined as systolic ≥140 mmHg and/or diastolic ≥90 mmHg.

^¶Defined as ≥1+ proteinuria and/or serum creatinine >1.5 mg/dL.

^#Defined as HDL <40 mg/dL or LDL >130 mg/dL.

^**N = 171 (131 women, 41 men).

Data presented are age- and sex-adjusted β coefficients from linear regression models. Each clinical variable was analyzed in a distinct model.