FIG. 5.

MV infection downregulates the hSLAM receptor. (A) Downregulation of hSLAM on CD4⁺ splenic T cells from nine tg lines and three non-tg mice, described in Fig. 4, following MV infection. Results were obtained 3 days after MV-Ed infection in vitro. Expression of hSLAM following MV infection (filled bars) and hSLAM expression in the absence of MV infection (open bars) are shown. Data were obtained by subtraction of percentages of expression in non-tg mouse lines from those in tg mouse lines. (B) hSLAM expression profile from CD8⁺ T lymphocytes with (filled bars) or without (open bars) MV infection.