. 2000 Aug;11(8):2743–2756. doi: 10.1091/mbc.11.8.2743

Table 4.

Summary of the phenotypes of the animals with various apm-1 and unc-101 genetic backgrounds

Genotype^a	Vulval phenotype
Wild-type	Wild type (WT)
let-23	Vulvaless
unc-101	WT
unc-101; let-23	WT or Greater than WT^b
unc-101; let-23; [Ex unc-101]	Vulvaless
unc-101; let-23; [Ex apm-1 hybrid]	Vulvaless
unc-101; apm-1 RNAi	WT or Greater than WT^b
let-23; apm-1 RNAi	WT or Greater than WT^b
wild type; [Ex apm-1∷GFP]	WT or Greater than WT^b

The exact genotypes of unc-101 and let-23 are unc-101(sy108) and let-23(sy1). Unc-101(sy108) is a putative null allele of unc-101, and let-23(sy1) is a reduction-of-function allele of let-23. [Ex gene] indicates that this gene was introduced as a transgene.

Unc-101 mutations can suppress the vulvaless phenotype of let-23(sy1) to yield wild-type vulval induction in some cases and greater-than-wild-type vulval induction in other cases (Lee et al., 1994). We found that apm-1 RNAi can also cause greater-than-wild-type vulval induction in various experimental schemes.