TABLE 8.
Sensitivities of HBsAg assays for detection of different HBV subtypes and mutants
| HBV subtype or mutant | Highest reciprocal dilution with a positive result
|
||||
|---|---|---|---|---|---|
| IMMULITE HBsAg or 2000 HBsAg | Elecsys HBsAg | Murex HBsAg (version 3) | Enzygnost HBsAg 5.0 | AxSYM HBsAg | |
| Subtypes | |||||
| adw2 | 100,000 | 400,000 | 100,000 | 100,000 | 400,000 |
| ayw4 | 440,000 | 440,000 | 6,400 | 6,400 | 440,000 |
| ayw2 | 1,000,000 | 1,000,000 | 200,000 | 200,000 | 1,000,000 |
| ayw3 | 128,000 | 128,000 | 128,000 | 32,000 | 128,000 |
| adr | 6,000 | 30,000 | 6,000 | 30,000 | 30,000 |
| adr/ayr | 4,000 | 32,000 | 4,000 | 4,000 | 32,000 |
| Mutants | |||||
| F134Y/G145R | 10 | 1a | 1,000 | 1a | NDb |
| P142S/G145R/N146D | 10 | —c | 1,000 | 1a | ND |
a
Undiluted.
b
ND, not determined.
c
—, not detected.