Table 3.
Relative Improvement of Individual Fibromyalgia Symptoms Associated with Antidepressants in Studies Using Similar Rating Scales*
| Symptom | Treatment Mean (95% Confidence Interval) | Placebo Mean (95% Confidence Interval) | Relative Improvement % |
|---|---|---|---|
| Fatigue | 5.0 (2.7 to 7.3) | 5.8 (4.5 to 7.3) | 14 |
| Trigger points | 10.6 (6.5 to 14.8) | 11.6 (7.2 to 16.1) | 9 |
| Pain | 4.3 (2.8 to 5.8) | 5.8 (3.8 to 7.8) | 26 |
| Sleep | 5.0 (3.2 to 6.9) | 6.5 (4.7 to 8.2) | 23 |
| Well-being | 5.2 (3.6 to 6.7) | 6.5 (5.0 to 7.9) | 18 |
*
Data included in this table are only from studies that had similar rating scales (e.g., visual analog scales from 0–10 or 0–100). Data was combined using the DerSimonian and Laird random effects model.