TABLE 1.
Comparison of EV NASBA and culture results by sample type
| Sample type | Total no. tested | No. of samples:
|
Total no. (%):
|
||||||
|---|---|---|---|---|---|---|---|---|---|
| NASBA+ culture+ | NASBA+ culture− | NASBA− culture+ | NASBA− culture− | NASBA invalida culture+ | NASBA invalida culture− | NASBA invalida | Positive by NASBA or culture | ||
| CSF | 102 | 21 | 10 | 0 | 69 | 0 | 2 | 2 (2) | 31 (30) |
| NP or throat | 29 | 5 | 0 | 3b | 13 | 0 | 8 | 8 (28) | 8 (28) |
| Rectal or stool | 32 | 8 | 0 | 0 | 19 | 2 | 3 | 5 (16) | 10 (31) |
| Otherc | 9 | 0 | 0 | 0 | 8 | 0 | 1 | 1 (11) | 0 |
| Total | 172 | 34 | 10 | 3b | 109 | 2 | 14 | 16 (9) | 49 (29) |
a
Samples testing invalid by NASBA were reextracted and reamplified at least once before the final result was obtained.
b
These culture isolates were ultimately identified as parechovirus and not enterovirus.
c
Four mouth swabs and one each brain biopsy sample, oral lesion swab, skin lesion swab, urine sample, and serum sample.