TABLE 3.

Symptoms and signs for patients with discordant positive results^a

Symptom or sign	Directigen assay, patient 1	LightCycler PCR							Culture
		Patient 1	Patient 2	Patient 3	Patient 4	Patient 5	Patient 6	Patient 7	Patient 1b	Patient 2	Patient 3	Patient 4
Symptoms
Characteristic
Sudden onset of sore throat		√	√		√	√	√	√		√		√
Pain on swallowing
Fever				√	√			√		√	√	√
Headache											√	√
Abdominal pain
Nausea and vomiting
Uncharacteristic
Coryza	√		√			√
Hoarseness				√								√
Cough		√		√	√						√
Diarrhea
Signs
Characteristic
Tonsillopharyngeal erythema	√		√	√	√	√	√	√			√	√
Tonsillopharyngeal exudate					√
Soft-palate petechiae         (“doughnut” lesions)
Beefy red, swollen uvula
Anterior cervical lymphadenitis			√		√
Scarlatiniform rash
Uncharacteristic
Conjunctivitis
Anterior stomatitis
Discrete ulcerative lesions

^aSymptoms and signs adapted from Dajani et al. (8).

^bThis patient had a history of recurrent sore throat but was asymptomatic and had no clinical findings at the time the throat swab for culture was obtained.