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. 2003 Jan;41(1):435–438. doi: 10.1128/JCM.41.1.435-438.2003

TABLE 1.

Association between sialidase or prolidase activity levels and LBW or PTD

Measured parameter(s) and/or vaginal colonization % Positivea
NTD (n = 116) LBW (n = 116) PTD (n = 86)
BV 14.6 20.7, 1.5 (0.9-2.6) 12.8, 0.9 (0.4-1.7)
G. vaginalis 36.2 42.2, 1.3 (0.8-2.0) 36.0, 1.0 (0.6-1.6)
BV and sialidase activity
    ≥+1 (cutoff) 9.1 15.7, 1.9 (1.0-3.4)b 7.1, 0.8 (0.3-1.9)
    ≥+2 1.0 3.5, 3.7 (0.9-15.1) 2.4, 2.5 (0.4-13.8)
G. vaginalis and sialidase activity
    ≥+1 (cutoff) 11.0 18.3, 1.8 (1.0-3.2)b 11.8, 1.1 (0.5-2.2)
    ≥+2 1.0 3.5, 3.7 (0.9-15.1) 2.4, 2.5 (0.5-13.8)
Sialidase activity
    ≥+1 (cutoff) 15.3 28.7, 2.2 (1.4-3.6)b 20.0, 1.4 (0.8-2.5)
    ≥+2 1.0 3.5, 3.7 (0.9-15.1) 2.4, 2.5 (0.4-13.8)
BV and prolidase activity
    ≥+1 (cutoff) 13.5 18.6, 1.5 (0.8-2.5) 12.0, 0.9 (0.4-1.8)
    ≥+2 0.2 2.7, 11.3 (1.2-109.6)b 1.2, 5.0 (0.3-81.5)
G. vaginalis and prolidase activity
    ≥+1 (cutoff) 23.4 31.0, 1.5 (0.9-2.3) 26.5, 1.2 (0.7-2.0)
    ≥+2 0.7 4.4, 6.4 (1.5-27.0)b 3.6, 5.2 (1.0-26.0)b
Prolidase activity
    ≥+1 (cutoff) 33.7 41.6, 1.4 (0.9-2.1) 34.9, 1.1 (0.6-1.7)
    ≥+2 1.0 4.4, 4.8 (1.3-18.0)b 3.6, 3.9 (0.8-17.6)
a

Where two values are given, the second value is the OR. Values in parentheses are 95% CIs.

b

P < 0.05.