TABLE 1.

Results of the detection of point mutations conferring resistance to clarithromycin by real-time PCR on 199 gastric biopsies compared with those of ɛ-Test performed on matched cultures

Phenotypic methoda	No. of biopsies	Real-time PCR result with:
		Wild type	A(2142/43)G	A(2142)C
Single genotype
S	64	+
R	87		+
R	1			+
R	3	+
S/R	2	+
Total	157
Multiple genotypes
R	30	+	+
R	2	+		+
R	3		+	+
R	1b	+	+	+
S	4	+	+
S/R	2	+	+
Total	42

^aPhenotypic method refers to the method used to determine susceptibility to clarithromycin (15). S, susceptible; R, resistant; S/R, susceptible by one method and resistant by a second method.

^bThe melting peaks of this biopsy are represented in Fig. 1.