Table 3.
Membrane-binding constants for SCAMP-derived peptides
| Peptide | PC (K, M−1) | PC/PS (3∶1) (K, M−1) |
|---|---|---|
| D-SL | 20 | 15 |
| E-SL | 328 | >104 |
| F-SL | 65 | 53 |
Membrane-binding constants determined for these peptides have an error of 10–20%. We were not able to make an accurate prediction of the binding of peptide E in PC/PS with EPR because the concentration of peptide needed for the assay significantly alters the membrane charge density at low lipid concentrations.