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Detection of NI-resistant influenza viruses in a mixture of wild-type and resistant viruses by the CL assay and FA-2. Wild-type and mutant viruses were mixed in the following ratios based on enzyme activity: 100:0, 80:20, 60:40, 40:60, 20:80, and 0:100. The results from one representative assay are displayed for each pair of viruses: R292K (A/H3N2), H274Y (A/H1N1), E119V (A/H3N2), R152K (B), and wild type (wt).
