Table 2.
Univariate Analysis of Risk Factors Associated with Trimethoprim-Sulfamethoxazole (TMP-SMX) Resistance on Urine Culture *
| >Variable | Resistant, % (n= 67) | Susceptible, % (n= 381) | Crude OR (95% CI) | p Value |
|---|---|---|---|---|
| Male sex | 12 (17.9) | 61 (16.0) | 1.1 (0.6, 2.3) | .70 |
| Age ≥65 years | 13 (19.4) | 41 (10.8) | 2.0 (1.0, 4.0) | .04 |
| Residence in long-term care facility | 4 (6.0) | 10 (2.6) | 2.4 (0.7, 7.7) | .15 |
| Use of urinary catheter | 12 (17.9) | 25 (6.6) | 3.1 (1.5, 6.5) | .002 |
| Upper tract infection | 34 (50.7) | 188 (49.3) | 1.1 (0.6, 1.8) | .83 |
| Diabetic | 9 (13.4) | 19 (5.0) | 3.0 (1.3, 6.8) | .008 |
| History of cancer | 4 (6.0) | 14 (3.7) | 1.7 (0.5, 5.2) | .38 |
| History of recurrent UTIs | 28 (41.8) | 99 (24.0) | 2.0 (1.2, 3.5) | .008 |
| Urologic abnormality | 10 (14.9) | 31 (8.1) | 2.0 (0.9, 4.3) | .08 |
| Neurologic abnormality | 13 (19.4) | 27 (7.1) | 3.2 (1.5, 6.5) | <.001 |
| Recently in hospital | 12 (17.9) | 32 (8.4) | 2.4 (1.2, 4.9) | .016 |
| Currently on antibiotic | 29 (43.3) | 26 (6.8) | 10.4 (5.6, 19.5) | <.001 |
| Currently or recently on TMP-SMX † | 29 (43.3) | 23 (6.0) | 11.9 (6.3, 22.6) | <.001 |
*
OR indicates odds ratio; CI, confidence interval; UTI, urinary tract infection; TMP-SMX, trimethoprim-sulfamethoxazole.
†
Use at any time within the past 3 months, including current use.