TABLE 3.
MICs of clarithromycin for MAC reported by four laboratories using microtiter dilution
| MAC strain | MIC (μg/ml) for isolate using:
|
|||
|---|---|---|---|---|
| Mueller-Hinton broth with 5% OADC
|
7H9 broth with casein
|
|||
| Mode (range) | % Agree- menta | Mode (range) | % Agree- ment | |
| JWT | 512 (512) | 100 | 512 (512) | 100 |
| JJL | 512 (128-512) | 77.8 | 512 (512) | 100 |
| 513 | 512 (256-512) | 100 | 512 (256-512) | 100 |
| 512 | 512 (512) | 100 | 512 (512) | 100 |
| 511 | 512 (512) | 100 | 512 (512) | 100 |
| 504 | 0.5 (0.25-512) | 82.9 | 2 (1-2) | 100 |
| 116 | 0.5 (0.25-512) | 90.9 | 2 (0.5-4) | 92.0 |
| 104 | 1 (0.5-2) | 100 | 8 (2-8) | 75.0 |
| 100 | 0.25 (0.25-1) | 88.9 | 4 (0.5-16) | 72.2 |
| 101R | 512 (64-512) | 91.7 | 512 (512) | 100 |
a
% Agreement, percentage of MICs in each 3-dilution range (mode ± log2) for isolates that produced sufficient growth. High-off-scale MICs were converted to the next-highest concentration; low-off-scale MICs were left unchanged. The following isolates did not grow for one or more tests: strain 504, once in Mueller-Hinton; strain 116, 3 times in Mueller-Hinton and 11 times in 7H9; strain 100, 9 times in Mueller-Hinton.