Table 5.
Univariate Analysis of the Relation of Cholesterol Level and Percentage Change in Cholesterol Level tothe Odds Ratio of Stroke in Cholesterol-Lowering Trials *
| Independent Variable | Dependent Variable | Correlation Coefficient r | Regression Coefficient β | p Value |
|---|---|---|---|---|
| Baseline total cholesterol, mg/dL | Fatal stroke | −.2495 | −.0035 | .7340 |
| Nonfatal stroke | .3960 | .0042 | .3126 | |
| Total stroke | .3186 | .0032 | .4010 | |
| Baseline LDL cholesterol, mg/dL | Fatal stroke | −.2572 | −.0040 | .7260 |
| Nonfatal stroke | .3524 | .0042 | .3682 | |
| Total stroke | .2801 | .0032 | .5754 | |
| Total cholesterol change, % | Fatal stroke | −.0364 | −.0038 | .9600 |
| Nonfatal stroke | −.2181 | −.0206 | .5824 | |
| Total stroke | −.1501 | −.0134 | .6966 | |
| LDL cholesterol change, % | Fatal stroke | −.0913 | −.0067 | .9044 |
| Nonfatal stroke | −.2849 | −.0184 | .4716 | |
| Total stroke | −.2164 | −.0133 | .5686 |
*
Regression analyses on stroke outcomes were performed in the natural log scale (ln OR). Regression weights were computed for each trial by the inverse of the square of their standard errors.