Histologic section of a fibroadenoma (hematoxylin-eosin staining, × 40). The cellular fibroblastic stroma, which resembles intralobular stroma, encloses glandular and cystic spaces lined by epithelium. Round and oval gland spaces, lined by either single or multiple cell layers, are present in other areas. The stroma in the connective tissue appears to have undergone a more active proliferation with compression on the gland spaces.